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| Player | Team | Goals |
|---|---|---|
| Cristiano Ronaldo | Real Madrid | 48 |
| L. Messi | Barcelona | 43 |
| Neymar | Barcelona | 22 |
| A. Griezmann | Atletico Madrid | 22 |
| C. Bacca | Sevilla | 20 |
| Aduriz | Athletic Club | 18 |
| Bueno | Rayo Vallecano | 17 |
| L. Suárez | Barcelona | 16 |
| K. Benzema | Real Madrid | 15 |
| Sergio García | Espanyol | 14 |
| Jonathas | Elche | 14 |
| J. Rodríguez | Real Madrid | 13 |
| Nolito | Celta Vigo | 13 |
| G. Bale | Real Madrid | 13 |
| Dani Parejo | Valencia | 12 |
| M. Mandžukić | Atletico Madrid | 12 |
| L. Vietto | Villarreal | 12 |
| C. Stuani | Espanyol | 12 |
| Paco Alcácer | Valencia | 11 |
| J. Larrivey | Celta Vigo | 11 |
| David Barral | Levante | 11 |
| C. Vela | Real Sociedad | 9 |
| Mikel Arruabarrena | Eibar | 9 |
| F. Caicedo | Espanyol | 9 |
| T. Hemed | Almeria | 8 |
| K. Gameiro | Sevilla | 8 |
| Víctor Casadesús | Levante | 8 |
| Y. El-Arabi | Granada CF | 8 |
| Juanmi | Malaga | 8 |
| P. Piatti | Valencia | 7 |