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New York Red Bulls finished 1st, Atlanta United FC 2nd.
| # | Team | P | W | D | L | Goals | Pts |
|---|---|---|---|---|---|---|---|
| 1 | New York Red Bulls | 34 | 22 | 5 | 7 | 62:33 | 71 |
| 2 | Atlanta United FC | 34 | 21 | 6 | 7 | 70:44 | 69 |
| 3 | Sporting Kansas City | 34 | 18 | 8 | 8 | 65:40 | 62 |
| 4 | Seattle Sounders | 34 | 18 | 5 | 11 | 52:37 | 59 |
| 5 | LAFC | 34 | 16 | 9 | 9 | 68:52 | 57 |
| 6 | FC Dallas | 34 | 16 | 9 | 9 | 52:44 | 57 |
| 7 | New York City FC | 34 | 16 | 8 | 10 | 59:45 | 56 |
| 8 | Portland Timbers | 34 | 15 | 9 | 10 | 54:48 | 54 |
| 9 | DC United | 34 | 14 | 9 | 11 | 60:50 | 51 |
| 10 | Columbus Crew | 34 | 14 | 9 | 11 | 43:45 | 51 |
| 11 | Philadelphia Union | 34 | 15 | 5 | 14 | 49:50 | 50 |
| 12 | Real Salt Lake | 34 | 14 | 7 | 13 | 55:58 | 49 |
| 13 | LA Galaxy | 34 | 13 | 9 | 12 | 66:64 | 48 |
| 14 | Vancouver Whitecaps | 34 | 13 | 8 | 13 | 54:67 | 47 |
| 15 | None | 34 | 14 | 4 | 16 | 47:53 | 46 |
| 16 | New England Revolution | 34 | 10 | 11 | 13 | 49:55 | 41 |
| 17 | Houston Dynamo | 34 | 10 | 8 | 16 | 58:58 | 38 |
| 18 | None | 34 | 11 | 3 | 20 | 49:71 | 36 |
| 19 | Toronto FC | 34 | 10 | 6 | 18 | 59:64 | 36 |
| 20 | Chicago Fire | 34 | 8 | 8 | 18 | 48:61 | 32 |
| 21 | Colorado Rapids | 34 | 8 | 7 | 19 | 36:63 | 31 |
| 22 | Orlando City SC | 34 | 8 | 4 | 22 | 43:74 | 28 |
| 23 | San Jose Earthquakes | 34 | 4 | 9 | 21 | 49:71 | 21 |
| Player | Team | Goals |
|---|---|---|
| J. Martínez | Atlanta United FC | 35 |
| Z. Ibrahimović | LA Galaxy | 22 |
| B. Wright-Phillips | New York Red Bulls | 20 |
| G. Zardes | Columbus Crew | 20 |
| M. Manotas | Houston Dynamo | 19 |