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| Player | Team | Goals |
|---|---|---|
| C. Benteke | DC United | 23 |
| L. Messi | Inter Miami | 21 |
| D. Bouanga | LAFC | 21 |
| L. Suárez | Inter Miami | 21 |
| D. Joveljić | LA Galaxy | 21 |
| C. Hernández | Columbus Crew | 20 |
| Gabriel Pec | LA Galaxy | 19 |
| C. Arango | Real Salt Lake | 19 |
| Riqui Puig | LA Galaxy | 17 |
| A. Martínez | New York City FC | 17 |
| F. Torres 2 | Orlando City SC | 17 |
| D. Gazdag | Philadelphia Union | 17 |
| M. Bogusz | LAFC | 16 |
| J. Rodríguez 0 | Portland Timbers | 16 |
| P. Musa | FC Dallas | 16 |
| B. White | Vancouver Whitecaps | 16 |
| L. Acosta 0 | FC Cincinnati | 15 |
| Evander | Portland Timbers | 15 |
| R. Gauld | Vancouver Whitecaps | 15 |
| Rafael Navarro | Colorado Rapids | 15 |
| J. Paintsil | LA Galaxy | 14 |
| S. Rodríguez | New York City FC | 14 |
| J. Morris | Seattle Sounders | 14 |
| Josef Martínez | CF Montreal | 14 |
| F. Mora | Portland Timbers | 14 |
| A. Gómez | Real Salt Lake | 13 |
| D. Rossi | Columbus Crew | 13 |
| L. Morgan | New York Red Bulls | 13 |
| S. Surridge | Nashville SC | 12 |
| A. Rusnák | Seattle Sounders | 11 |